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Despite a substantial reduction in global maternal deaths
2019-06-28
Despite a substantial reduction in global maternal deaths due to postpartum haemorrhage between 1990 and 2013 (from 71 295 to 44 190), this condition continues to be the main cause of maternal mortality worldwide. In sub-Saharan Africa and south Asia, many women still deliver at home without a skill
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br Discussion Pocket hematoma is a frequent
2019-06-28
Discussion Pocket hematoma is a frequent complication in the early stages following cardiac device na+/ca2+ exchanger and its incidence has been reported to be 0.9–22% [11–16,18–22]. In this study, 161 patients underwent cardiac device surgery and 10 (6.2%) of these patients had bleeding complica
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Clearly there are limitations to the current study These inc
2019-06-28
Clearly there are limitations to the current study. These include the single centre, retrospective nature of the study as well as its relatively small sample size compared with the randomised data. However, the duration of follow up is considerably longer than these trials (Table 1). In conclusion,
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In summary we have established an animal model of
2019-06-28
In summary, we have established an animal model of human NB bone metastasis in which COX-2/PGE2 plays a critical role. We provide pre-clinical data supporting the use of COX-2 inhibitors in the treatment of bone metastases in NB. Conflict of interest statement Introduction Desmoplastic fibrom
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Cerrone et al reported that the mechanism of CPVT was
2019-06-28
Cerrone et al. reported that the mechanism of CPVT was due to delayed afterdepolarization‐induced triggered activity in a focal Purkinje network in a knock-in (RyR2) mouse [36]. In addition, chemical ablation of the RV endocardial cavity with Lugol׳s solution, which selectively destroys the Purkinje
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Immediate rollout of an effective and safe short course trea
2019-06-28
Immediate rollout of an effective and safe short-course treatment regimen is essential for the attack phase of the visceral leishmaniasis elimination programme, which aims to reduce the incidence to less than one case per 10 000 Miglitol at risk. A single-dose liposomal amphotericin B regimen, whic
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The long term goal of independence
2019-06-28
The long-term goal of independence of recipients and sustainability of projects must remain at the forefront of all programmes. The post-2015 Sustainable Development Goals (SDGs) have been criticised as being too general and impractical, and as we move into the SDG era this study has identified a ne
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br Basis and methodology of
2019-06-27
Basis and methodology of DCE-MRI DCE-MRI images are performed by using injecting low-molecular-weight gadolinium chelated contrast agent with a constant, stable rate. The contrast agent is carried by blood flow into the tissue, causing increased signal intensity (SI) of the T1-weighted images due
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Common and rare SCN A variants may contribute to AF
2019-06-27
Common and rare SCN10A variants may contribute to AF susceptibility [59,60]. SCN10A mutations (R14L and R1268Q) cause a loss of function of Nav1.5 current, which is expected to reduce excitability and lead to the development of the arrhythmogenic substrate responsible for BrS and AF. A common varian
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The regular meridians are distributed symmetrically on
2019-06-27
The 12 regular meridians are distributed symmetrically on the left and right sides of the body, and run along their fixed courses. The temperature of paired bilateral acupoints shows symmetry and correlation to the left and right sides. One member of our research group, Bing Xiong, compared the skin
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Our group then carried out
2019-06-27
Our group then carried out a study to determine the substrate sites and arrhythmogenic mechanisms of the BrS [29]. We found that all our BrS patients had abnormal low voltage, fractionated late potentials exclusively clustering in the anterior aspect of the RVOT epicardium and not seen anywhere else
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Based on the methodology used in previous studies the
2019-06-27
Based on the methodology used in previous studies, the EGM source for the Wavelet algorithm has been nominally programmed as the Can-RV coil EGM [13]. As the nominal EGM source includes the generator, myopotentials induced due to body motion or other muscle activity are likely to influence the arrhy
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It is noteworthy that even with low
2019-06-27
It is noteworthy that, even with low tumor burden in these patients following CR, peak value at CR status is still a useful indicator for OS, both in the whole cohort, and more importantly, in the intermediate-risk subgroup. Slope is mainly determined by tissue vascularization and perfusion, but cap
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br Predictors of benefit from bisphosphonates Randomized con
2019-06-27
Predictors of benefit from bisphosphonates Randomized control studies of adjuvant BP therapy in early breast cancer show benefit related to “low estrogen states” [1,2,5,6]. Unfortunately, thus far, only one study has assessed systemic estrogen levels to substantiate these results. This is clearly
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br To see how the
2019-06-27
To see how the quantity of osteosarcoma in vitro studies developed overtime, we set out to systematically identify all the drugs that have been tested on osteosarcoma Terbutaline Sulfate in vitro in the past two decades. A PubMed search strategy was compiled which can be found in Supplementary dat
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