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br Materials and methods br Results
2019-07-02
Materials and methods Results and discussion Conclusions In the present study, we have shown the important role of miR-204-5p in C2C12 myoblast differentiation. Overexpression of miR-204-5p inhibited myogenic differentiation and decreased the formation of slow-twitch myofibers, whereas miR-
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In addition to PGC transcriptional co repressors such as NCO
2019-07-02
In addition to PGC1α, transcriptional co-repressors such as NCOR and RIP140 participate in oxidative muscle remodeling induced by exercise, whereby reductions in their expression and the resulting de-repression of downstream TFs activates oxidative gene expression (Seth et al., 2007, Yamamoto et al.
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(+)-Aphidicolin Here two labs that helped characterize these
2019-07-02
Here, two labs that helped characterize these two pathways have worked together to further test whether these apparently parallel pathways from β-AR to CaMKII-RyR might be related in series. Much of the work leading to the Epac pathway involved measurement of Ca sparks as an index of SR Ca leak, oft
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The key difference between the membrane zymography and class
2019-07-02
The key difference between the membrane zymography and classical measurements of enzyme activities in soil slurries is the enzyme-substrate accessibility. Classical enzyme assays maximize access of substrate to all potentially reactive enzyme sites by ensuring sample destruction and detachment follo
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br Method Detailed study protocol was reported previously
2019-07-01
Method Detailed study protocol was reported previously. The ULTIMATE- HFrEF trial was approved by the Institutional Review Board of our hospital, and the study drug, udenafil, was approved as Investigational New Drug for treatment in patients with chronic HFrEF by Ministry of Food and Drug Safety
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The distribution of dental treatments and the number
2019-07-01
The distribution of dental treatments and the number of treated teeth within each age group were also analyzed. The 6-years-old group had the lowest mean number of teeth treated by stainless-steel crown (SSC) and the lowest number undergoing pulp therapy (pS63845 what and, when compared against 20
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br Methods br Results A total of
2019-07-01
Methods Results A total of 2136 cases, including 614 controls, and 707 LAA, 375 SVO, and 440 HICH cases, were enrolled in this study. Clinical parameters between the control individuals and patients with different stroke subtypes are listed in Table 1. The average age and serum HDL-C level wer
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The electrophysiological mechanisms underlying high frequenc
2019-07-01
The electrophysiological mechanisms underlying high frequency activity observed in the PLA during SRAF could be reentry (rotor) or focal discharges (triggered activity). To discriminate between these mechanisms, we perfused ryanodine (10–40μM) or caffeine (5mM) to abolish calcium overload-mediated t
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br Case report A year
2019-07-01
Case report A 50-year-old female presented with splenomegaly (24 cm) and pancytopenia in Mar. 2014. A bone marrow biopsy revealed hypocellular marrow (GSK2269557 structure of R-COP (Fig. 3). Further 5 cycles of cytotoxic therapy with standard dose R-CEOP (rituximab; cyclophosphamide; epirubicin;
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In contrast to adults PBL in children is regarded as
2019-07-01
In ANA 12 to adults, PBL in children is regarded as a clinical entity that is distinct from its adult counterpart. Like many other pediatric malignancies, PBL is considered a systemic disease in children. In small retrospective studies, PBL in children is characterized by rapid progression, a highe
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Quercetin dihydrate molecular In September a high level meet
2019-07-01
In September 2011, a high-level meeting of the UN called for a concerted global response to the growing challenge of non-communicable diseases (NCDs). Subsequently, in 2013, the World Health Assembly adopted a WHO-generated action plan and set a target of 25 × 25: a 25% reduction in premature mortal
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br Introducci n De una manera muy
2019-07-01
Introducción De una manera muy esquemática y lipoxygenase inhibitor grandes trazos, podemos diferenciar al menos cuatro momentos en los estudios sobre la democracia en América Latina en el último medio siglo, según algunos problemas predominantes. Las limitaciones y quiebres democráticos, las pos
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Susana Huenul Colicoy realiz un
2019-07-01
Susana Huenul Colicoy realizó un estudio sobre este proceso de intercambios que llevaron Silydianin of los diálogos para la redacción de esa ley, en el que nos informa del encuentro de 2005 que duró ocho meses y en él se reunieron ocho dirigentes lafkenche y su equipo técnico con los representantes
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Se antes Jos Mart em Cuba
2019-07-01
Se antes José Martí em Cuba, em 1891, com Nuestra América, e logo, em 1900, José Enrique Rodó com Ariel, propugnavam uma alteridade diversa dos Estados Unidos para os latino-americanos pós-independência, por exemplo, Dipesh Chakrabarty, em Provincializing Europe, reelaborou essas e aquelas consignas
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c75 br Discussion There is an important need
2019-07-01
Discussion There is an important need for new treatment options for AML in elderly patients. Their frailty imposes limitations upon the aggressiveness of the treatment which can be administered [6,24]. In addition, the poor prognostic disease features often seen in this c75 mean that refractorine
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