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br Conclusion br Introduction The morphological variability
2021-02-27
Conclusion Introduction The morphological variability of aquatic plants is well documented, and in some cases has seriously constrained taxonomic resolution (Sculthorpe, 1967, Santamaría, 2002). Many of these variations are caused by the extensive phenotypic plasticity of aquatic plants, but t
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br Related work Goal of this section is to show
2021-02-27
Related work Goal of this section is to show related work focused on methods useful to assess the reliability of clustered COTS-based systems. Connelly et al. [1] propose an approach to delineate safety assurance for the use of COTS OS in safety-related applications, which must fall in SIL2. The
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br Introduction The cys loop
2021-02-27
Introduction The cys-loop ligand gated ion channels (LGICs) are membrane-bound proteins mediating fast transduction from chemical to electrical signals at neuronal synapses and neuromuscular junctions [1], [2]. Each subunit that makes up the pentameric LGIC architecture possesses a dicysteine br
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rsv In some pancreatic and non pancreatic tissues the chlori
2021-02-27
In some pancreatic and non-pancreatic tissues, the chloride and calcium channels are heavily regulated by phosphorylation by protein kinases, such as PKC, cyclic AMP-dependent protein kinase (PKA), PKCaMKII, PI3K and protein tyrosine kinases [7,36,37]. Since the interaction of triterpenes with recep
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Epitope analyses of AT AA and ET AA indicate
2021-02-27
Epitope analyses of AT1-AA and ET-AA indicate that the p2x7 of both autoantibodies are located at the second extracelluar loop of both receptors. The specific epitopes for both autoantibodies are similar to what was reported previously in a cohort of patients from Brazil [6] and for AT1-AA also fro
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br Acknowledgments Denise Fernandes acknowledges a postdoc f
2021-02-27
Acknowledgments Denise Fernandes acknowledges a postdoc fellowship (SFRH/BPD/34289/2006) from the Portuguese Fundação para a Ciência e Tecnologia (FCT) of the Ministry of Science and Technology of Portugal. This work was supported by the Spanish National Plan for Research (Project Ref. CGL2011-24
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We obtained two bands in RT PCR for detection of
2021-02-27
We obtained two bands in RT-PCR for detection of SERPIN1-FOSB fusion when Taq DNA polymerase was used (Fig. 3A). Genuine RT-PCR product of SERPIN1-FOSB fusion was proved to be the shorter one (733 Ademetionine pairs) by sequencing, and the longer band (863 base pairs) was shown to be derived from n
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Another interesting finding regarding substrate selectivity
2021-02-27
Another interesting finding regarding substrate selectivity of iPLA2-VIA in whole cellular systems stems from the observation that some of the major species hydrolyzed by the enzyme contain a 16:1 fatty BMN-673 at the sn-2 position [57,119], raising the possibility that iPLA2-VIA may constitute a m
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DDR is one of two
2021-02-27
DDR1 is one of two, non-integrin tyrosine kinase receptors activated by collagen. Although DDR1 has five isoforms (1a, 1b, 1c, 1d, 1e) generated by alternative splicing, only DDR1a and 1b have active kinase domains, whereas DDR2, encoded by a distinct gene, has one isoform (Vogel et al., 2006). Coll
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In conclusion our findings demonstrated
2021-02-27
In conclusion, our findings demonstrated that S1PC augments HMOX1 expression in a NO-dependent manner, and its effects are associated with the enhancement of BACH1 degradation. In addition, S1PC and NO potentially degrade BACH1 based on the observation that nuclear degradation of BACH1 differs from
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External factors such as protein partners can also activate
2021-02-27
External factors, such as protein partners, can also activate DUBs by either reinforcing the stimulatory effects of intramolecular factors or by other means. The intramolecular activation of the USP7 CD by its HUBL domain is allosterically potentiated by external factor GMP synthase (GMPS), which co
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ganciclovir Studies of LRRK tagged with green fluorescent pr
2021-02-26
Studies of LRRK2 tagged with green fluorescent protein revealed the presence of monomeric LRRK2 in the ganciclovir of living cells, while LRRK2 oligomers were found in the proximity of the plasma membrane, suggesting that both oligomerization status and compartmentalization of LRRK2 defines its func
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Sensory gating describes a filter mechanism protecting
2021-02-26
‘Sensory gating’ describes a filter mechanism protecting the central nervous system from sensory overload by inhibiting behaviorally irrelevant input (Boutros et al., 2004, 2008). This permits Safingol to a changing contextual environment (Fruhstorfer et al., 1970; Grunwald et al., 2003). Auditory
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No orthologs could be found
2021-02-26
No orthologs could be found in our B. oleracea BAC library for AtCk1/2, which could mean that it is unique to Arabidopsis, or that we failed to detect it in our library. However, the second possibility is unlikely considering that Southern blotting analysis with four restriction enzymes disclosed fr
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Located on the fore tarsals of the front pair of
2021-02-26
Located on the fore-tarsals of the front pair of legs, the Haller’s organ is presumed central to tick chemosensation. Recent genomic, transcriptomic and proteomic investigations have identified several families of transmembrane proteins in the forelegs of ticks that are likely involved in olfactory
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