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histamine receptor antagonist br Conclusion Leukocytes adhes
2022-03-26
Conclusion Leukocytes adhesion to endothelial cells is one of the most critical event in the inflammatory response. In presented paper using a relevant model of adhesion we have demonstrated that histamine influence eosinophils adhesion to endothelium. This effect appears to be mediated by H4 his
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Introduction Histamine H Imidazol yl ethanamine mol w
2022-03-26
Introduction Histamine (2-(1H-Imidazol-4-yl)ethanamine), mol.w. 111.15 g/mol belongs to biogenic amines, which arise in foodstuffs from amino acids by action of microorganism´s or tissue enzymes. Histamine (HA) is formed from the amino Z-IETD-FMK L-histidine by action of enzyme histidine decarboxyl
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It is not established if ONOO
2022-03-26
It is not established if ONOO− also induces tyrosine nitration of ANT and affects VDAC1 and ANT interaction, as well as the interaction of VDAC1 with HK II, all of which are events that may lead to altered mitochondrial and cellular function. Thus, in this study we examined tyrosine nitration of bot
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br Materials and methods br
2022-03-26
Materials and methods Results Discussion The innate immune system plays an important role in protecting against IAV infections. However, the virus has the ability of escaping the innate immune system. Activating or enhancing an innate immune response before or during a viral infection will
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Sugar gliders and hedgehogs are insectivores and actively
2022-03-26
Sugar gliders and hedgehogs are insectivores and actively seek arthropods in nightly forays. It is suspected that Triatoma were not feeding on the sugar gliders and hedgehogs, but rather were being eaten. The oral route of infection is often nonfatal and induces a carrier state in South American di
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The following are the supplementary data related to this art
2022-03-26
The following are the supplementary data related to this article. Introduction Target therapies have achieved significant gains in the fight against cancer, however, they are still a long way from providing generally curative treatments for the majority of cancers. Targeted agents can be used wi
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A few animal and cell culture
2022-03-26
A few animal and cell culture studies have been reported that the reason of HCV-related hepatic steatosis in CHC infection is mainly HCV core protein (Chang et al., 2007; Perlemuter et al., 2002; Ferré, 2004). HCV core protein inhibits activities of microsomal triglyceride transfer protein (MTP) and
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While phosphorylation site motifs are typically described in
2022-03-26
While Telatinib site motifs are typically described in terms of residues that promote phosphorylation, negatively selected residues can also be an important component of substrate recognition. Such ‘forbidden’ resides can act as a filter to prevent phosphorylation of a site by the ‘wrong’ kinase, w
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In the present study we aimed to investigate the
2022-03-25
In the present study, we aimed to investigate the effect of a common dairy and beef genetic background on the mRNA α-mangostin of the AdipoQ system and GPR109A in different adipose depots and liver. Materials and Methods Results Comparing fat masses between families (fat-type vs. lean-type co
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Given that we planned to isolate the GluN GluN
2022-03-25
Given that we planned to isolate the GluN1/GluN3A receptor by immunoaffinity chromatography using a Myc epitope tag on GluN3A, we first checked that the tag does not affect the functional properties of the receptor. To do this we co-transfected HEK-293 cells with DNA encoding WT GluN1 and either WT
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The amino hydroxy methyl isoxazolepropionic acid AMPA recept
2022-03-25
The α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic SB 290157 trifluoroacetate salt (AMPA) receptors are related ionotropic glutamate receptors (iGluRs) that mediate fast excitatory neurotransmission, and are also typically heteromeric ion channels, composed of GluA2 subunits in conjugation with Gl
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Ajzenman et al reported improved stability
2022-03-25
Ajzenman et al reported improved stability and postural parameters in ASD children after EAT. Other authors presented similar findings,61, 62, 63, 64 although the studies were conducted among children with CP, and reported improved muscle symmetry,, stability of the head and the trunk, motor functio
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Studies examining cerebral glucose metabolism in MDD using F
2022-03-25
Studies examining cerebral glucose metabolism in MDD using 18 F-fluorodeoxyglucose in positron emission tomography (FDG-PET) showed altered regional glucose metabolism in MDD (Dunn et al., 2002, Kennedy et al., 2001, Kimbrell et al., 2002, Saxena et al., 2001). In a recent meta-analysis by Su and co
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br Some general considerations on anterior
2022-03-25
Some general considerations on anterior pituitary cell type, models, sex and drugs Historically, real-time analysis of native endocrine anterior pituitary cell excitability has been somewhat limited and thus much of the pioneering work on anterior pituitary cell excitability and stimulus-secretio
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In a mouse model of hyperhomocysteinemia
2022-03-25
In a mouse model of hyperhomocysteinemia (a risk factor for the development of vascular dysfunction) it has been shown that myoendothelial communication is enhanced due to increased expression of Cx37 and IK1 NAD/NADH Quantitation Colorimetric Kit [], allowing the propagation of endothelial signals
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