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To further address the mechanism of Didox
2024-12-04
To further address the mechanism of Didox’s suppressive effects on mast cell activation, FceRI receptor cy3 excitation emission and downstream transcription factor induction were assessed. We found that Didox had no effect on FceRI surface expression, and thus concluded that Didox effects must be oc
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However relatively little information is available
2024-12-03
However, relatively little information is available concerning the biochemical properties and other features of such enzymes in Taeniid species. In the current report, a M17 leucine aminopeptidase gene of T. pisiformis (TpLAP) was cloned and expressed, and its enzymatic activity, biochemical propert
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Some members from the AAAP family namely the AUX
2024-12-03
Some members from the AAAP family, namely the AUX1 and the LAX proteins, transport auxin instead of amino acids [48]. While there is some structural relationship between IAA and Trp, the substrate recognition characteristics seem different for these proteins: the auxins do not have any amino group o
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Lee et al have demonstrated that APPL associates with AdipoR
2024-12-02
Lee et al. have demonstrated that APPL1 associates with AdipoR1 in Hek293 Estradiol Cypionate australia where both proteins have been overexpressed with suitable tags [16]. In contrast to recent data the formation of this complex is not enhanced by exogenous adiponectin [16], [33]. Knock-down of AP
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trans-AUCB We also investigated the transmittance of actin
2024-12-02
We also investigated the transmittance of actin polymerized with and without ABP. The presence of actin in the solution results in an increment in turbidity as other proteins provided trans-AUCB features [21], [32]. While G-actin showed a transmittance peak positioned at 241 nm, F-actin exhibited a
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br Autophagy in cancer br Phytochemicals as
2024-12-02
Autophagy in cancer Phytochemicals as a valuable source of autophagy modulation agents Epidemiological studies demonstrated that there is a strong association between diet and human cancer mortality so that daily consumption of phytochemicals declines the incidence of different types of cancer
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br Experimental section br Acknowledgements br Introduction
2024-12-02
Experimental section Acknowledgements Introduction DJ-1 is a highly conserved, homodimeric protein that was originally cloned as an oncogene capable of transforming Oxamic acid receptor in cooperation with activated ras[1]. DJ-1 is over-expressed in multiple tumor types and is positively co
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br Experimental br Acknowledgment This paper
2024-12-02
Experimental Acknowledgment This paper was financially supported by the Project Funded by China Postdoctoral Science Foundation (2017T100186), Natural Science Foundation of Liaoning Province (20170540858), General Scientific Research Projects of Department of Education of Liaoning Province (20
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Nile Red Plant tissues were thought to be natural
2024-12-02
Plant tissues were thought to be natural sources containing different types of antioxidant compounds (tocopherols, ascorbic acid, carotenoids, and phenolic compounds). As a general classification, antioxidants were grouped as vitamins (ascorbic acid, tocopherols), carotenoids (condensed tannins, xan
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br Acknowledgements br Introduction Microbial enzymes
2024-11-29
Acknowledgements Introduction Microbial enzymes have gained interest for their widespread uses in industries and medicine owing to their stability, catalytic activity, and ease of production and optimization than plant and animal enzymes (Singh et al., 2016). Microbial aminopeptidases (amino-a
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The preferential expression of ALOX B
2024-11-29
The preferential expression of ALOX15B in human macrophages may explain why human genetic studies investigating the association of ALOX15 with cardiovascular disease did not show consistent results. Two rare functional polymorphisms have been characterized in the ALOX15 gene, which leads to increase
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br Potential and established risk factor for
2024-11-29
Potential and established risk factor for Alzheimer’s Disease The only way to overcome the above mentioned limitations is the identification of risk factors, which, taken together, can reliable predict the development of AD. Age and ApoE4 are established non-modifiable risk factors for AD. The ri
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Accumulating evidence suggest that patients with advanced
2024-11-29
Accumulating evidence suggest that patients with advanced -positive NSCLC are at increased risk of VTE or coagulation disorders during the course of their disease, indicating that cancer genotype might play a role in the occurrence of cancer-related thromboembolism . Here we report the case of a pat
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A rate limiting step in the generation of kynurenine
2024-11-29
A rate-limiting step in the generation of kynurenine and xanthurenic LBH 589 is the oxidation of N-formyl-kynurenine to l-kynurenine via indolamine 2,3-dioxygenase (IDO) or tryptophan dioxygenase (TDO). IDO and/or TDO knockdown decreases and ectopic over-expression increases production of endogenou
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br Functions essentially consisting in transport of
2024-11-29
Functions essentially consisting in transport of substrates across plasma membranes Direct activation of neurotransmitter transporters elicits responses in neurons As previously mentioned (Section 2.1), nerve terminals handling classical transmitters possess transporters able to (re)capture se
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