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br Resource table Resource details The
2018-11-08
Resource table. Resource details The study was approved by the Singhealth ethics committee (protocol number SHSIBC-2014-031), and written informed consent was obtained from the patient. 2ml of peripheral blood sample was obtained from a male 64-year-old Parkinson\'s disease patient carrying a he
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Using similar approach additional mESC lines could be derive
2018-11-08
Using similar approach, additional mESC lines could be derived using a Pitx3::GFP reporter mouse (Zhao et al., 2004) and another aSYN mouse model of Parkinson\'s disease, expressing human WT SNCA (Westerlund et al., 2008) (data now shown). These mESC lines (Table 1) can be used to study human SNCA-
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br Materials and methods br Author disclosure statement br
2018-11-08
Materials and methods Author disclosure statement Acknowledgments This study was supported by fund from National Medical Research Council (NMRC) of China to SZ (fund number: 30400447) and HW (fund number: 30500548). Resource table. Resource details To engineer a biallelic mutation in t
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br Results br Discussion In previous studies we derived peri
2018-11-08
Results Discussion In previous studies, we derived pericytes (Kusuma et al., 2013) and both hiPSC syn-vSMCs and hiPSC con-vSMCs (Wanjare et al., 2013a). In performing direct comparisons between these perivascular cell derivatives, we observed numerous differences that enable the study of human
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A key element of the culture
2018-11-08
A key element of the culture conditions is the balanced combination of growth factors and signaling molecules (e.g., EGF, bFGF, IGF, insulin, transferrin, and Rock inhibitor), which apparently generates an artificial androgen-independent PESC microenvironment that promotes the self-renewal and maint
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The activity of CXCL through CXCR receptor has
2018-11-08
The activity of CXCL12(5-67) through CXCR3 receptor has been shown before (Denoyer et al., 2012; Zhu et al., 2009). Here we aimed to confirm this finding using CXCL9, a natural ligand of CXCR3. NSCs pre-treated with CXCL9 were not susceptible to the CXCL12(5-67) apoptotic effects. The effect of CXCL
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c Kit RP http www apexbt com media diy images
2018-11-08
c-Kit+ RPCs are distributed from the central to the peripheral regions of the retina, but not in the ciliary bodies, which were previously proposed to house retinal progenitors (Cicero et al., 2009; Martinez-Navarrete et al., 2008). These data suggest that c-Kit+ RPCs are a distinct population of PS
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Concurrent with the application of gene editing
2018-11-08
Concurrent with the application of gene editing in human cells, the generation of human induced pluripotent stem boldenone undecylenate (iPSCs) was described (Takahashi et al., 2007; Yu et al., 2007). iPSCs possess properties of self-renewal and pluripotency that are similar to those of embryonic st
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Taken together these findings indicate that basal to luminal
2018-11-08
Taken together, these findings indicate that basal-to-luminal differentiation can occur in prostate organogenesis, pathogenesis, and ex vivo assays, but rarely during normal tissue homeostasis. Thus, it has been unclear to what extent the plasticity of endogenous adult prostate basal Cy5.5 hydrazide
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Induced pluripotent stem cell iPSC technology holds great pr
2018-11-08
Induced pluripotent stem cell (iPSC) technology holds great promise for future autologous cellular therapies for vascular diseases (Tavernier et al., 2013). However, a major concern is the availability of approaches to differentiate iPSCs into large quantities of functional VSMCs for research and th
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The empirical analysis was specifically targeting two hypoth
2018-11-07
The empirical analysis was specifically targeting two hypotheses regarding the relationship between contextual generalized trust and individual immunization acceptance. Using a multilevel logistical procedure, the empirical analysis supports the pitavastatin Supplier that contextual generalized tru
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With similarities and differences in social economic and pol
2018-11-07
With similarities and differences in social, economic, and political contexts in Canada and the United States, it Rapalink-1 has been suggested that comparing these two countries holds important insights for understanding how structural determinants, such as social policies and economic resources,
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Grau looks beyond this and affirms that Spanish universities
2018-11-07
Grau (2012) looks beyond this and affirms that Spanish universities are not within the actual political priorities of policy makers, and that one of the purposes of the European Commission is for Spanish universities to implement tools of strategic management to become more competitive and responsib
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The effective process is chemically
2018-11-07
The effective process is chemically based and similar to an acid–base neutralization reaction, rather than biologically dominated where the uptake and sequestering of heavy metals occurs directly in the algae. It is necessary to maintain physical separation of the algal colony from the effluent stre
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In Understanding Business Cycles Lucas states The same type
2018-11-07
In Understanding Business Cycles, Lucas states: The same type of criticism appears in Unemployment Policy. In this paper – which is mainly a criticism of the useless (according to Lucas) concepts of full (as also involuntary) unemployment and the use of economic policy in the quest to attain it. Lu
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