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Based on these preliminary clinical results with
2019-04-15
Based on these preliminary clinical results with low-dose, intermittent zoledronic acid, Hu et al. conducted a randomized phase II clinical study in order to clarify the role of metronomic low-dose zoledronic acid. Sixty breast cancer patients with bone metastases were randomized to receive either 1
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MCs play a key role
2019-04-15
MCs play a key role in the maintaining homeostasis of tissues where they reside by participating in tissue repair, reactions against viral and parasitic infections, and aiding in the regulation of various cell types such as dendritic cells, T cells, and macrophages. In addition, MCs are involved in
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Hill and colleagues estimate that globally about million CI
2019-04-15
Hill and colleagues\' estimate that, globally, about 1·5 million (95% CI 1·2–1·8) children aged 5–14 years died in 2010. This finding is somewhat higher than the total estimated by the UN of 1·3 million, although the UN estimate is within the investigators\' CI. However, their estimate is 87% higher
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br Alegato y ret rica de
2019-04-15
Alegato y retórica de la violencia en la Brevíssima relación de la destruyción de las Indias En el año 1552 fray Bartolomé de las Casas, en Sevilla, se ocupa de dar ikk pathway la imprenta ocho de sus principales escritos, entre ellos la Brevíssima relación, compuesta diez años antes: “Y pareciól
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Adan and Natale in a
2018-11-15
Adan and Natale (2002), in a study conducted in Barcelona involving 2135 individuals with age between 17 and 30 years, verified association between the male gender and eveningness [40]. In the same year, in Brazil, Hidalgo et al. (2003) investigated 318 individuals of the same age, obtaining the sam
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In Weinstock and Walters of RLS
2018-11-15
In Weinstock and Walters [8], 43% of RLS-associated conditions have also been associated with systemic iron deficiency. Iron is distributed heterogeneously in different regions and WST Cell Proliferation Colorimetric Assay Kit plus cells; brain iron homeostasis is required for its normal function
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The results for the second reform show that in the
2018-11-15
The results for the second reform show that, in the short-term, the capital stocks in both sectors (k and ) remain close to the initial steady state values, while employment grows by 3.65% in labor-intensive sector and decreases by 2.89% in the capital-intensive sector. These short-term effects end
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The increase observed for the sub indices related
2018-11-15
The increase observed for the sub-indices related to the stages of planning and negotiation (SI), approval (SII) and execution of the budget (SIII) over the period of analysis did not change the relative position of these sub-indices with respect to fiscal discipline: the budgetary institutions that
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We found that the STX R Q variant has
2018-11-15
We found that the STX1 R/Q variant has decreased phosphorylation of Ser14, a key residue involved in the functional regulation of STX1 (Khelashvili et al., 2012; Dubois et al., 2002). STX1 in this hypo-phosphorylated state fails to support DAT-mediated reverse transport of DA without inhibiting DA u
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br Introduction The epidermal permeability
2018-11-15
Introduction The epidermal permeability barrier is one of the most crucial protective functions of the skin and is primarily mediated by stratum corneum lipids and differentiation-related proteins. Stratum corneum lipids consist mainly of an equal molar ratio of cholesterol, fatty acids, and cera
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br Introduction The elderly population in Turkey has now bec
2018-11-15
Introduction The elderly compund w in Turkey has now become the “aged” population. In Turkey, the elderly create 7.7% of the total population, and, according to population projections, this proportion will reach 10.2% (8.6 million older people) in 2023. Materials and methods Multiple compari
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br Acknowledgments br Introduction Psoriatic skin lesions ar
2018-11-15
Acknowledgments Introduction Psoriatic skin lesions are characterized by histological evidence of inflammation, abnormal keratinocyte proliferation/terminal differentiation, and dermal angiogenesis. Although the etiology of psoriasis remains unknown, it is clear that an interaction among genet
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br Hyperimmunoglobulin E syndrome HIES Job s Syndrome is a
2018-11-15
Hyperimmunoglobulin E syndrome (HIES, Job\'s Syndrome) is a rare primary immunodeficiency disease characterized by a clinical triad of recurrent staphylococcal abscesses, pneumonia, and pneumatoceles, with a tendency for recurrent pyogenic infections and elevation of serum immunoglobulin E (IgE) l
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In conclusion the results of this study suggest
2018-11-15
In conclusion, the results of this study suggest that daily supplementation of curcumin extracts has a positive beneficial effect against chemically induced colonic preneoplastic progression in rats induced by DMH, which provide an effective dietary chemopreventive approach to disease management. Be
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Finally by sorting the Wnt off cells we obtained a
2018-11-14
Finally, by sorting the “Wnt-off” cells, we obtained a striking increase in the number of reprogrammed NANOG+ clones, thus clearly identifying the “Wnt-off” state as an early reprogramming marker. It is interesting to note how different the roles of TCF3 and TCF1 are in the control of somatic cell
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