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Collapsed across groups vACC activation did not show a signi
2018-11-09
Collapsed across groups, vACC activation did not show a significant correlation with age (r(48)=0.23, p=0.1). However, when assessing these correlations in each group separately, activation in the vACC ROI sphere correlated significantly with age in TD youth (r(17)=0.464, p=0.045), but not UAS or AS
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GDC-0994 br Consideraciones finales Al respecto hay que reco
2018-11-09
Consideraciones finales Al respecto hay que recordar que este problema de vulnerabilidad a los ciclos económicos externos orientó buena parte de los esfuerzos de la política económica aplicada en nuestro país durante varias décadas del siglo xx, sobre todo a partir de las décadas de los años trei
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The following are the supplementary data
2018-11-09
The following are the supplementary data related to this article. Author Contributions Conflicts of Interest Acknowledgments This work was supported by grant R01 AI098132 (R.L.G.) awarded by the National Institute of Allergy and Infectious Diseases. The transgenic mouse and DNA sequencing
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The bioenergetic system of the brain
2018-11-09
The bioenergetic system of the GS-9620 is compromised early in the progression of AD and is evident during the prodromal (preclinical) stage of the disease (Mosconi, 2005; Mosconi et al., 2006, 2009b; Reiman et al., 1996, 2004; Yao et al., 2009, 2011b; Brinton et al., 2015; Moreira et al., 2006; Li
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Dietary calcium intake is critical for the calcium homeostas
2018-11-08
Dietary calcium intake is critical for the calcium homeostasis of bone. Supplementary diets containing calcium with average recommended dietary allowance for children increase bone mineral density (BMD) and reduce the risk of fracture [93]. As reviewed in the previous section, calcium homeostasis is
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br Acknowledgments br Introduction Mouse
2018-11-08
Acknowledgments Introduction Mouse embryonic stem (ES) ampar can give rise to all somatic cell types and germ cells in a regulative manner and are thereby defined as pluripotent. They are thought to have ‘no pre-determined programme’. However, whether or not an ES cell represents a ‘tabula ra
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It is evident that within our
2018-11-08
It is evident that within our model, compressed collagen gels play a key role in driving limbal stem cell growth and phenotype. Our results suggest that these changes are due to the increased mechanical properties of compressed collagen gels with improved surface nanostructure. More importantly LEC
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br Material and methods br
2018-11-08
Material and methods Acknowledgments We are grateful to D. Trono (Lausanne, Switzerland) for the plasmid pMD2.G and psPAX2. We thank Brigitte Jenewein for her excellent technical assistance with the confocal laser-scanning microscopy and the flow cytometry analysis. This work was supported by
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scd1 br Results br Discussion Mammalian primordial germ
2018-11-08
Results Discussion Mammalian primordial germ scd1 are considered unipotent, giving rise only to the gametes. Indeed, the sperm and egg represent two of the most overtly differentiated cell phenotypes. Yet, these two specialized cells regain access to the entire embryonic and extraembryonic di
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A current limitation in studying neuronal
2018-11-08
A current limitation in studying neuronal differentiation using cultured NSPCs is that the rate of neuronal differentiation of adult NSPCs is rather incomplete: when standard protocols of growth-factor withdrawal are used, only 8%–30% of NSPC progeny differentiate toward the neuronal lineage (as mea
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Having confirmed that the Nanog iPSCs expressed
2018-11-08
Having confirmed that the Nanog−/− iPSCs expressed key markers of pluripotency, we sought to determine the extent to which the global expression profile of Nanog−/− iPSCs recapitulated that of ESCs. To this end, we performed RNA sequencing (RNA-seq) of two replicates each of control Nanog+/+ ESC, iP
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To determine if subepithelial cells such as SEMFs are
2018-11-08
To determine if subepithelial cells, such as SEMFs, are a required physiologic Wnt source, we used Myh11-Cre mice. Myh11-encoded smooth-muscle myosin heavy chain is expressed in much of the intestinal subepithelium (Wirth et al., 2008). To define the precise expression domain, we crossed Myh11-Cre t
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This finding is consistent with our
2018-11-08
This finding is consistent with our observations in human fetal RG cells (Mo and Zecevic, 2008), indicating that in both cell populations Pax6 affects proliferation as well as neuronal fate. Numerous studies have reported the successful transplantation of hESC into rodent brains (Kelly et al., 2004
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br Materials and methods br Results br Discussion
2018-11-08
Materials and methods Results Discussion Acknowledgments This work was supported by a stem cell fund from Pennsylvania State University Eberly College of Science and grants from National Institute of Health (NIMH083911 and NIMH092740) to GC. FHG was supported by Transformative R01MH09574
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Comparative gene expression analysis of ex
2018-11-08
Comparative gene expression analysis of ex vivo expanded lung stromal naag also showed that the activation of an epithelial-supportive phenotype was associated with the reactivation of genes related to lung development, epithelial morphogenesis and angiogenesis. This suggests that the signaling path
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