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br An estimated million babies are born preterm
2019-05-22
An estimated 15 million babies are born preterm annually. Preterm birth complications account for more than 15% of deaths in children younger than 5 years and survivors often have long-term consequences with respect to their health, growth, and psychosocial functioning. The most beneficial interve
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Si los sicarios y sus
2019-05-22
Si los sicarios y sus cárteles ejercen un oficio de tinieblas, donde “madrugar” es uno de los ejes rectores de un México violento, zafio, “kafkiano” y pulsante de impunidad, para Juan Villoro: Circunscrito por el crimen, la miseria y la muerte, el tema de una juventud cercada por la violencia es t
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R406 Introduction Acute myeloid leukemia AML is a rare disea
2019-05-21
Introduction Acute myeloid leukemia (AML) is a rare disease afflicting annually 3–4 persons per 100,000 individuals. With a median age at diagnosis of 67 years, this disease is far more common in the elderly [1]. In this age group, AML has a particularly dismal outcome with less than 5% of the pati
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The imbalances in the current
2019-05-21
The imbalances in the current R&D system were the subject of the 2012 report of WHO\'s Consultative Expert Working Group on Research and Development (CEWG). The CEWG recommended a global binding agreement that provides a needs-driven and evidence-based framework for R&D, guided by the core principle
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Numerous animal studies have demonstrated beyond doubt that
2019-05-21
Numerous animal studies have demonstrated beyond doubt that effective inhibition of osteoclastogenesis or osteoclast function significantly reduces metastatic tumour growth in bone [13–20]. Likewise, clinical trials in patients with non-metastatic or metastatic cancers established that treatment wit
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Introduction Neuroblastoma NB which arises
2019-05-21
Introduction Neuroblastoma (NB), which arises from embryonal neural crest cells, is the most common extra-cranial solid tumor of childhood and accounts for more than 15% of all child cancer death [1,2]. Patients with NB frequently manifest disseminated disease at first visit and prognosis of these
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In the univariate subgroup analysis the factors that predict
2019-05-21
In the univariate subgroup analysis, the factors that predicted reduced survival were increased age, significant mitral regurgitation (≥ grade 2), and creatinine level (Table 4). After multivariate analysis, (+)PES followed by ICD smad pathway was a strong predictor of reduced mortality, along with
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br Conclusions br Conflict of interest br Introduction
2019-05-21
Conclusions Conflict of interest Introduction Arrhythmogenic right ventricular cardiomyopathy (ARVC), previously called arrhythmogenic right ventricular dysplasia (ARVD), is an inherited disease characterized by right ventricular degeneration and ventricular arrhythmias. ARVC is one of the
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Los antecedentes que en este
2019-05-21
Los antecedentes que en este sentido se agradecen son las referencias a los géneros —forense y epidíptico— que convergen en los discursos de quienes presenciaron los acontecimientos de la Conquista. Herencias del medioevo: la tradición bíblica, fábulas y el imaginario pagano, detrás de los que exist
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pde-5 inhibitors Ethiopia is faced with challenging circumst
2019-05-21
Ethiopia is faced with challenging circumstances. It is a low-income country, with a gross domestic product estimated by the International Monetary Fund at US$570 per person in 2014, and 66% of the pde-5 inhibitors living on less than US$2 per day in 2011—rates that are even lower than the averages
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K03861 El libro de William Crawford publicado en traducido
2019-05-21
El libro de William Crawford publicado en 1944, traducido en 1966, y las obras de Leopoldo Zea de 1949 y de 1965, aunque de muy distinto carácter y alcance, suscitaron primero un artículo de Oscar Kubitz en 1960, después un ensayo de Salomon Lipp en 1975, y, finalmente, otro artículo de frank Spindl
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En realidad el texto con el que Granada concluye
2019-05-21
En realidad el texto, con el que Granada concluye su Introducción al Símbolo de la Fé, consta de diez capítulos en los que se insiste en no explicar Radicicol los que quieran convertirse de manera inmediata “los misterios del cristianismo, porque no creen aún, sino que hay que llevarlos por la vía d
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De acuerdo con el historiador argentino la independencia de
2019-05-21
De acuerdo con el historiador argentino, la independencia de las colonias españolas en América es el resultado de una degradación del poder español que había comenzado desde 1795. En primera instancia, el poder de la Corona española se hacía cada vez más lejano, pues la pérdida de la guerra de Españ
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HOBt HBeAg positive patients older than years with persisten
2019-05-21
HBeAg-positive patients older than 40 years with persistently high or high to normal ALT levels may be diagnosed with significant hepatic necroinflammation or fibrosis. During treatment, the clinical significance of timing of HBeAg loss or seroconversion remains unclear. However, a longer duration o
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Since antithrombotic therapy for patients with AF
2019-05-20
Since antithrombotic therapy for patients with AF is rapidly changing with the increasing use of dabigatran, rivaroxaban, and apixaban, some of the primary issues that will influence the future revision of various guidelines (HRS [Heart Rhythm Society], ESC [European Society of Cardiology], ACC [Ame
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