• br Results br Discussion HSPCs

  2018-10-22

  

  Results Discussion HSPCs include rapidly cycling progenitor cells that produce vast numbers of effector cells on a daily basis. It was therefore not unexpected to find that genes involved in EHT 1864 and metabolic growth were enriched in HSPCs, but surprisingly, we also discovered that many o

• br Experimental Procedures br Author Contributions br

  2018-10-22

  

  Experimental Procedures Author Contributions Acknowledgments We thank Clive N. Svendsen for providing the human fetal cortical neural stem cells, Rachel Harker and Scott Muller for exceptional primate husbandry, Cedric Bardy and the Salk Institute for providing the BrainPhys medium used in

• br Introduction Both the excess obesity and the lack

  2018-10-20

  

  Introduction Both the excess (obesity) and the lack/atrophy (lipodystrophy) of adipose tissue are associated with altered metabolism and lead to major diseases. In particular, the prevalence of obesity-linked diseases has increased worldwide during the past 10years (Savage et al., 2007). The chro

• Previous research has shown that

  2018-10-20

  

  Previous research has shown that spaceflight causes suppression of erythropoiesis (Davis et al., 1996), reduction in circulating red blood cells, increased platelet formation, and reduction in plasma volume resulting in a condition referred to as spaceflight anemia (Smith, 2002), however the molecul

• Finally the potential contribution of CD b cells to

  2018-10-20

  

  Finally, the potential contribution of CD11b+ AVE 0991 cost to the regenerative microenvironment highlights the experimental challenges in defining the mechanism of lung growth. The distinct transcriptional profiles of the CD11b+ cells, and their migration into different anatomic compartments, sugg

• br Materials and methods br Acknowledgements

  2018-10-20

  

  Materials and methods Acknowledgements Mef2c-AHF-Cre mice were generously provided by Dr. Brian L. Black. We thank Mamen Martín and Sandra Rodríguez (Molecular Cytogenetics Unit, CNIO) for technical advice; and the Imaging Core Facility for the confocal analysis (CIMA, University of Navarra).

• Finally by sorting the Wnt off cells we obtained a

  2018-10-20

  

  Finally, by sorting the “Wnt-off” cells, we obtained a striking increase in the number of reprogrammed NANOG+ clones, thus clearly identifying the “Wnt-off” state as an early reprogramming marker. It is interesting to note how different the roles of TCF3 and TCF1 are in the control of somatic cell

• br Results br Discussion We highlight the generation of

  2018-10-20

  

  Results Discussion We highlight the generation of human functional haploid spermatids from human SSCs of cryptorchid patients. Cryptorchidism is the most common etiologic factor for azoospermia in adults. Among men with untreated bilateral cryptorchidism, 89% eventually develop azoospermia (Ch

• br Materials and methods br Resource table

  2018-10-20

  

  Materials and methods Resource table Material and methods Introduction While increasingly effective for treating childhood cancers, chemotherapeutic agents and radiotherapy are known to have deleterious effects on the gonads of prepubertal boys (Schrader et al., 2001; Wallace, 2011). As

• Cyt 387 manufacturer Both natural and synthetic approaches h

  2018-10-20

  

  Both natural and synthetic approaches have been used to generate fully defined hPSC culture substrates. ECM proteins such as vitronectin and laminins 511 and 521 have been shown to maintain hESC pluripotency and self-renewal (Braam et al., 2008; Domogatskaya et al., 2012; Miyazaki et al., 2012; Rodi

• br Introduction In mammals cells from the blastocyst stage c

  2018-10-20

  

  Introduction In mammals, cells from the glucose transporter stage can be used to form embryonic stem (ES) cell lines that can self-renew in culture while maintaining the ability to differentiate into cells of the three germ layers (Reubinoff et al., 2000). Directed in vitro differentiation proto

• A question arising from this work

  2018-10-20

  

  A question arising from this work is whether development sets the stage for the early pathophysiological abnormalities in HD and whether we can identify candidate pathways or genes that will restore neuronal homeostasis and protect striatal MSNs halting disease progression. We believe the black and

• It is often pointed out

  2018-10-20

  

  It is often pointed out that tumor Tedizolid HCl manufacturer can escape immune cells by changing their antigenicity through the modification of targeted peptide sequences or reduction of HLA-molecule expression (Schreiber et al., 2011). This is usually the case when immune therapies with antigen-sp

• Main Text br Acknowledgments I have

  2018-10-20

  

  Main Text Acknowledgments I have been fortunate to work with tremendous mentors, colleagues, and students throughout my career and I am grateful for their past and current support. Research in my laboratory is supported by the NIH, the New York Stem Cell Foundation as a New York Stem Cell Founda

• br Experimental Procedures br Author Contributions br

  2018-10-20

  

  Experimental Procedures Author Contributions Acknowledgments This work was supported by grants from the Ministerio de Ciencia e Innovación (Grant SAF2012-38914), Plan Nacional de I + D + I, Spain and the Agència de Gestió d’Ajuts Universitaris i de Recerca (AGAUR) (Grant 2014 SGR229), Depar

15168 records 1011/1012 page Previous Next First page 上5页 10111012